Picus Duo+
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Hands- & adjustment-free operation
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Ultra-fast spectral tuning in ms
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Multicolor SRS & CARS imaging
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TPEF & SHG ready
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All-fiber laser design
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Compact & air-cooled
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Integrated beam adjustment
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Automated power control
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Plug & play for microscopes
Use cases
Advancing research & care
Our versatile laser technologies deliver rich-contrast, label-free imaging across many fields, improving life science and healthcare.
Observing cell behavior
Lets you watch how cells act and interact in real time.
Lipid metabolism studies
Helps analyze fat processing inside live cells without labels.
Pharmacokinetics
Tracks how drugs move and change within cells over time.
Cancer research
Reveals detailed cellular changes important for cancer research.
Features
+Function. +Comfort. +Focus on science.
Experience compact precision with full computer control, enabling fast, flexible, and accurate chemical analysis.
Upgrade any microscope with high-speed, full-spectrum SRS
The Picus Duo+ enhances our renowned Picus Duo with added automation and beam shaping to upgrade laser scanning microscopes. This all-in-one unit minimizes setup time and ensures reproducible, high-contrast SRS imaging, allowing you to focus on your science rather than the hardware.
With two overlapped picosecond beams (Pump and Stokes), it covers the full Raman range from 700 to 3100 cm⁻¹ and switches wavelengths in milliseconds. Its all-fiber, air-cooled design requires no water cooling or vibration isolation and provides full computer control over tuning, modulation, delay, and power.
Seamless integration
All critical adjustments, from beam overlap to power regulation, are already built in, allowing you to start imaging with confidence and minimal setup time. Whether upgrading an existing microscope or starting from a new configuration, we support you throughout the process to ensure full mechanical, optical, and electronic compatibility.
Unmatched speed
Picus Duo+ delivers fast, label-free imaging across the full Raman fingerprint (700–3100 cm⁻¹), capturing lipids, proteins, and nucleic acids in a single scan. Millisecond-speed tuning enables multicolor imaging and 3D reconstructions with sharp, sub-cellular resolution without waiting or staining.
Multimodal imaging
Optimized for SRS but also supporting CARS, SHG, TPEF, and fluorescence, the Picus Duo+ enables multimodal imaging on a single platform. Capture complementary chemical, structural, and functional information from your samples without switching systems.
Advanced detection
Equipped with Refined’s low-noise, balanced detection technology, the Picus Duo+ improves signal-to-noise ratios up to threefold and allows imaging speeds up to ten times faster. Fully integrated with software control, it ensures stable, high-speed SRS imaging with minimal setup.
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