Noctua SRS imaging system

The all-in-one SRS imaging system

Our Noctua delivers seamless all-in-one SRS imaging with integrated laser, scanning-microscope, and control, capturing live cells label-free in real time with exceptional resolution and minimal phototoxicity.

Noctua SRS imaging system
  • Hands- & adjustment-free operation

  • Ultra-fast spectral tuning in ms

  • Multicolor SRS & CARS imaging

  • TPEF & SHG ready

  • All-fiber laser design

  • Compact & air-cooled

  • Fully integrated imaging system

  • Plug & play installation

  • Label-free chemical imaging

Use cases

Advancing research & care

Our versatile laser technologies deliver rich-contrast, label-free imaging across many fields, improving life science and healthcare.

Observing cell behavior

Lets you watch how cells act and interact in real time.

Lipid metabolism studies

Helps analyze fat processing inside live cells without labels.

Pharmacokinetics

Tracks how drugs move and change within cells over time.

Cancer research

Reveals detailed cellular changes important for cancer research.

Features

Next-generation laser imaging systems

Designed to support modern research and diagnostic workflows.

Fully integrated and ready to use SRS imaging

Our Noctua is a fully integrated, automated SRS imaging system for fast, label-free chemical imaging of cells and tissue. It provides an easy and accessible way to bring high-performance SRS technology into your lab – no staining, no complex setup required.

With full Raman spectral access, millisecond tuning, and a plug-and-play design, Noctua is ideal for molecular pathology, biomarker discovery, and live cell studies. Compared to conventional systems, it offers a streamlined, user-friendly alternative without the cost or complexity.

Effortless operation

Noctua removes the complexity of traditional SRS imaging. With synchronized lasers, scanners, detectors, and software in one integrated system, there's no alignment, cooling, or setup required. Just start the software and begin imaging – as easily as with a standard widefield microscope.

Noctua system for effortless operation

Unmatched speed

Noctua delivers fast, label-free imaging across the full Raman fingerprint (700–3100 cm⁻¹), capturing lipids, proteins, and nucleic acids in a single scan. Millisecond-speed tuning enables multicolor imaging and 3D reconstructions with sharp, sub-cellular resolution without waiting or staining.

Sample courtesy of D. Kapsokalyvas (Maastricht University)

High-contrast detection

Powered by Refined’s low-noise balanced detection, Noctua suppresses laser noise and boosts signal-to-noise ratios by a factor of three, enabling faster, clearer imaging. The detection system is fully integrated, ensuring stability, reliability, and minimal setup.

High-contrast detection on Noctua
Multimodal flexibility with Noctua

Multimodal flexibility

Noctua goes beyond SRS. It supports CARS, SHG, TPEF, and widefield imaging in a single platform, delivering structural, chemical, and functional contrast from the same sample without labels or dyes.

Sample courtesy of V. Kučikas (Maastricht University)

Smart software

Noctua’s dedicated software unifies control of lasers, scanners, detectors, and acquisition in one intuitive interface. From z-stacks to hyperspectral scans, and from region selection to spectral analysis, it simplifies advanced imaging workflows and makes high-end SRS as accessible as fluorescence microscopy.

Noctua smart software interface
Seamless upgrade module for existing microscopes

Seamless upgrade

Already have a microscope? Noctua is available as a scanner module that connects directly to the camera port of inverted widefield systems. No alignment, optical table, or cooling required. Just plug in and start acquiring high-contrast, label-free molecular images within minutes.

Contact

Try for yourself

Request a free demo or talk to our team – no strings attached.